Concise Dictionary of Pharmacological Agents: Properties and by Ian Dr Morton;Judith M. Hall;I. K. Morton

By Ian Dr Morton;Judith M. Hall;I. K. Morton

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Drugs effecting a cure. Tissue schizonticides are used to effect a radical cure, and are effective against parasites in the liver. Only 8-aminoquinolines, primaquine, have this action. Drugs used in prophylaxis'. g. chloroquine, dapsone, doxycycline, mefloquine, proguanil and pyrimethamine, and often in combinations. Drugs used to prevent transmission. g. primaquine, proguanil and pyrimethamine. Cook. C. (1990) Parasitic Disease in Clinical Practice, Springer-Verlag, Berlin. M. et al. (1992) Halofantrine.

J. , 328, 349-350. Wallace. L. (1994) Mechanisms of nonsteroidal antiinflammatory drug (NSAID) induced gastrointestinal damage - Potential for development of gastrointestinal tract safe NSAIDs. Can, J. Physiol. , 72, 1493-1498. P. (1996) The chemotherapeutic effects of HVK + inhibitors on Helicobacter pylori infection. Pharmacol. , 69, 79-83. ANTIVIRAL AGENTS There are relatively few drugs that are active against viruses and their effectiveness is often restricted to preventive or disease-limitation treatment.

Rifampicin is an antibacterial antibiotic, which also has extensive use in the treatment of tuberculosis. It is used in combination with other drugs. Clofazimine is a red dye of complex structure, thought to work by an action on DNA. C. et al. (1988) Chemotherapy of leprosy. Annu. Rev. Pharmacol. , 28, 231-245. H. (1995) Leprosy (Hansen's disease), in Mandell. L. , New York, pp. 2243-2250. ANTIMALARIALS are used to treat or prevent malaria. The disease is caused by infection of the red blood cells with a protozoan organism of the genus Plasmodium, which is carried by the Anopheles mosquito.

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